Loved since 1908. For dogs of all sizes. With real bone marrow. With calcium. Wholesome goodness with real bone marrow. Wholesome & Tasty: Delicious treats that you can feel good about giving. With Real Bone Marrow: Tasty and nutritious. With Calcium: Rich in calcium to help maintain strong teeth and bones. www.milkbone.com. If you have any questions about Milk-Bone dog snacks, please call 1-888-Milkbone (645-5266), weekdays. Please include the product manufacturing code in consumer correspondence. Produced in Buffalo, New York, USA.